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Contraindications and Drug Interactions Absolute contraindications include Wilsons Disease or other copper metabolism disorders (risk of dangerous copper accumulation), known copper allergy or hypersensitivity (risk of severe allergic reactions), and pregnancy/breastfeeding (no safety data available for systemic use)

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(15) People who drink alcohol excessively or who are alcoholics have lower levels since this affects gut health, how glutathione is synthesized, and how much the body needs

The challenge with making sense of these associations is that Ive not seen a single study in a pregnant population that is not also supplemented with high doses of folic acid

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